Mainz is the state capital and largest city, while other major cities include Ludwigshafen am Rhein , Koblenz , Trier , Kaiserslautern , and Worms. Rhineland-Palatinate became part of the Federal Republic of Germany in , and shared the country's only border with the Saar Protectorate until it was returned to German control in Rhineland-Palatinate has since developed its own identity built on its natural and cultural heritage, including the extensive Palatinate winegrowing region, its picturesque landscapes, and many castles and palaces. It was formed mainly from the southern part of the Prussian Rhine Province the Regierungsbezirke of Koblenz and Trier , from Rhenish Hesse , from the western part of Nassau and the Bavarian Rhenish Palatinate minus the county of Saarpfalz. The Joint German-Luxembourg Sovereign Region Gemeinschaftliches deutsch-luxemburgisches Hoheitsgebiet is the only unincorporated area of the state of Rhineland-Palatinate.
Flow of cerebrospinal fluid regulates neural stem cell division
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