Irradiation plan of a head and neck tumor. Squamous cell carcinomas of the head and xucht HNSCC are usually only diagnosed at an advanced stage and thus have a relatively poor prognosis. One cause may be human papillomavirus HPVbut the main cause is tobacco smoking and excessive consumption of high-percentage alcohol. This could offer an opportunity for personalized treatment. To investigate this question, the researchers examined cancer tissues from two independent tissue sample collections: In the analysis, the researchers focused on miRNAs: She shares the first authorship with Dr.
Both are heading a working group in the Research Unit Radiation Cytogenetics. Out of all of the miRNAs, the researchers were able to identify five miRNAs whose expression predicted the course of the disease and the risk of recurrence. In addition, it is now possible to search for the genes that are influenced by the five miRNAs and find out whether they represent worthwhile target structures for therapy. Inthe scientists had already identified a miRNA signature that makes it easier to estimate the course of the disease in brain tumors.
Unlike protein synthesis, however, RNA is not needed for the construction of molecules. On the contrary, many miRNAs are able to prevent the build-up of certain proteins by degrading the corresponding RNA blueprint.
It is estimated that currently about 2, different miRNAs are known. To achieve this, it investigates the interaction of genetics, environmental factors and lifestyle.
The focus is on clarifying the mechanisms associated with radiation-induced carcinogenesis and radiation sensitivity of tumour Dating emden Hannover er sucht sie. The aim of this research is to find biomarkers associated with radiation-induced tumours in order to develop personalized radiation therapy for the stratification of patients.
Just over 2, beds are available to its International internet dating Simple and Express ECOs with Aras specialist clinics, twelve institutes and six Datinv, and its 49 interdisciplinary centres.
Of a total of 9, employees, around 1, are doctors and 3, are nursing staff. Munich University Hospital has been a public-law institution since Helmholtz - Gemeinschaft Deutscher Forschungszentren.
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